A16z Sees Top of Leading Mega Round in Ex-OpenAI CTO’s AI Startup, Thinking Machines Lab

In a daring gambit that highlights the high-stakes competition in the generative AI arena, Silicon Valley giant Andreessen Horowitz (A16z) is said to be in serious discussions to lead a huge early-stage funding round in Thinking Machines Lab, the artificial intelligence startup by ex-OpenAI Chief Technology Officer Mira Murati. As estimated by four sources who are privy to the situation, the round would be valuing the company at an eye-popping $10 billion—without any revenue, mind you, nor any public product offerings—since it was only launched two months ago.

If finalized, the deal would place Thinking Machines Lab among the most valuable AI startups in the world, signaling investor confidence in both Murati’s leadership and the broader long-term potential of AI infrastructure development. The interest from A16z, one of the most influential venture capital firms in tech, suggests that the startup has struck a chord with investors hungry to back the next wave of innovation in artificial intelligence.

The Mira Murati Factor
Mira Murati, the highly regarded and influential figure whose departure from OpenAI in late 2024 created a shockwave in the AI community, was instrumental in developing models like GPT-4 and ChatGPT. Her exit led to speculation as to what direction she would move next.

Now, with Thinking Machines Lab, she seems to be following a new direction—one that attempts to rectify some of the key shortcomings and dangers of today’s-generation AI systems. As per initial remarks made by the company, the startup has focused on creating AI that is “safer, more reliable, and built for broader, more inclusive applications.” Industry insiders familiar with the early plans of the startup define it as an initiative to bring world-leading research closer to practical applications while retaining strong focus on safety and transparency.

What Sets Thinking Machines Lab Apart
In its infancy, Thinking Machines Lab has created quite a buzz throughout the AI space and investing communities. The company, as sources indicate, is building a team of world-class AI researchers, safety engineers, and systems engineers. The company has already poached a number of significant hires from OpenAI, Google DeepMind, and academia, generating even more interest in the firm’s prospects.

Murati’s startup reportedly aims to rethink the design of foundational models from the ground up. Rather than racing to release the most powerful model possible, the company is said to be focused on modular, interpretable systems that offer greater control and predictability. These goals have positioned Thinking Machines as an emerging leader in what some are calling “third-wave AI”—a shift from mere performance to robust alignment and ethical integration.

One of the key areas of focus for the company is said to be the creation of AI models that can safely work alongside humans in high-risk settings such as healthcare, education, and scientific research—areas where existing AI systems tend to fail because they lack reliability or explainability.

The Importance of the $10 Billion Valuation
A valuation of $10 billion would be almost unheard of for such a young company, especially one that has not yet shipped a product or made revenue. It says a lot about the hunger for high-potential AI startups, as well as the influence of founder pedigree and vision in securing capital.

Andreessen Horowitz’s likely leading position in the round lends extra gravitas. A16z has been one of the most outspoken advocates of AI innovation, investing in a number of high-profile startups in the field including Character.AI, Perplexity AI, and xAI. Their likely investment in Thinking Machines Lab would not only provide capital but also strategic guidance, access to a massive network of partners, and clout in the wider tech ecosystem.

The round will likely feature the involvement of some other leading firms and sovereign wealth funds, but those terms are still being negotiated.

A Crowded Yet Evolving AI Landscape
The startup landscape of AI has grown more competitive with billions invested in startups vying to build the next generation of generative AI models. Although companies like OpenAI, Anthropic, Cohere, and Inflection AI have already raised enormous amounts, the foray of Thinking Machines Lab is setting a higher benchmark by highlighting transparency, safety, and ease of use right from day one.

Many investors and observers see this focus as a necessary evolution of the field. As AI systems become more powerful and integrated into society, concerns around bias, misinformation, safety, and ethical use have moved to the forefront. Murati’s approach appears to be a response to this growing sentiment—that AI must not only be advanced but also responsibly built and deployed.

Conclusion
Thinking Machines Lab, founded by Mira Murati, has already become one of the most closely followed participants in the AI field. With the backing of a strong vision and potentially enormous capital from Andreessen Horowitz, the startup is already set to make its mark despite having only been around for months.

The reported $10 billion valuation, while eye-popping, reflects both investor faith in Murati’s leadership and the belief that the next generation of AI startups will need to prioritize safety, ethics, and broad applicability as much as raw computational power.

If Thinking Machines Lab delivers on its promise, it could redefine what successful AI innovation looks like—not just in terms of technology, but in terms of values. As the race for AI dominance continues, Murati’s new venture could be the one that shifts the narrative from speed to sustainability.

Bhavesh Mishra

Bhavesh Mishra is a skilled writer at Arise Times, focusing on the latest stories about startups, technology, influencers, and inspiring biographies. With a passion for storytelling and a sharp eye for detail, Bhavesh delivers engaging content that highlights emerging trends and the journeys of changemakers. His writing aims to inform, inspire, and connect readers with the people and ideas shaping today’s world.

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